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It's an essence extracted from someone's skull at the point of death.

It's highly euphoric and addictive. You don't feel anything while it's inside of you.

Amber Sweet (Paris Hilton) is addicted to it in Repo! The Genetic Opera. She has a sexual relationship with G-Rob who she gets it from.

It's generally used before getting surgery.

Though, it's highly abused.
(From Zydrate Anatomy)
GRAVEROBBER
Zydrate comes in a little glass vial.

SHILO
A little glass vial?

CROWD
A little glass vial!

GRAVEROBBER
And the little glass vial goes into the gun like battery.
And the Zydrate gun goes somewhere against your anatomy
And when the gun goes off, it sparks and you're ready for surgery.
Zydrate by NoahtheGreat October 31, 2008
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Zydrate is a fictional drug. In the movie Repo! The Genetic Opera, Zydrate -a potent opioid extracted from dead bodies- is manufactured by GeneCo. as a prescription painkiller. Zydrate is injected with a Zydrate-Gun which uses an electric current to enhance the drug's analgesic effect.
Graverobber: Zydrate comes in a little glass vile.

Shilo: A little glass vile?

Junkies: A little glass vile!

Graverobber: And the little glass vile goes into the gun like a battery... And the Zydrate-Gun goes somewhere against your anatomy... And when the gun goes off it sparks and you're ready for surgery.
Zydrate by LJenna January 5, 2009
Related Words
A mixture of Mountain Dew Voltage and ecstasy (MDMA). Named after and inspired by the fictional drug of the same name from the movie Repo! The Genetic Opera.
Hey dude, I made some zydrate from some ecstasy we got at the club the other night.
Zydrate by Jehav July 2, 2009
Zydrate is a rare type of drug that helps relieve pain. It also gets you a bit high. Mainly scalpel sluts use this drug.
Amber Sweet is addicted to the knife, so in order for her to relieve her pain, she buys Zydrate from a Grave Robber.
Zydrate by xxRepoManxx January 16, 2009
It is said of the situation where a person has the bad luck to make contact with his testicles against an undefined surface or object, intentioned or not.
Given the nature of the word, it is more appropriate to design cases where the interaction is made with a moving object, for example, a ball.
Although it is extremely painful for the victim, it tends to be considerably funny to people who witness it.
Today in the baseball game the pitcher took a nutshot; the baseball hit him in the nuts.

Man, I just watched the funniest nutshot video ever.
Nutshot by Uberflaven March 1, 2009
Word of the Day on June 26, 2026

Nerd neck 

A "human" that spends so much time playing video games that their posture is level nerd neck. Everytime anyone goes tryhard they hunch down and their neck gets longer there fore a nerd neck is always hunched down cause they're always going try hard. In other words a nerd neck is a try hard, since their neck is 100% longer than the average human being due to playing too many video games and taking them serious, nerd necks are not even considered human anymore but something more sad. Nerd necks are often found on fortnite, their natural habitat usually being tilted towers.
What a fucking nerd neck!

He is building so fast, nerd neck!

Looser more like a nerd neck ha!
Nerd neck by D Sandwich Maker February 5, 2019
Word of the Day on June 25, 2026

love peace and chicken grease 

"another of sayin peace out or good bye"
Talk to ya later......Love, Peace, and Chicken Grease
Word of the Day on June 24, 2026