Just one of many slang terms for the drug known as ecstasy. Ecstasy is illegal substance in pill form that usually contain MDXX and are (unfortunately) often pressed/cut with other substances (fillers) which can cause harmful side effects to the mind and body.
The characteristics of these pills may vary.
A: "What kind of e-pills you got?"
B: "Some Single,Double,Triple,Quadruple,Quintuple - Red/Blue/Yellow/Green/White/Purple/Orange/Black/Brown/Pink/Magenta/Speckled - Dolphins/Ladies/Poke Balls/unmarked/etc."
A: "What's in them?"
B: "I dunno but they're good"
A: "OK, I'll take a boat"
B: *thinking* (Oh shit! An undercover.)
It is said of the situation where a person has the bad luck to make contact with his testicles against an undefined surface or object, intentioned or not.
Given the nature of the word, it is more appropriate to design cases where the interaction is made with a moving object, for example, a ball.
Although it is extremely painful for the victim, it tends to be considerably funny to people who witness it.
Today in the baseball game the pitcher took a nutshot; the baseball hit him in the nuts.
Man, I just watched the funniest nutshot video ever.