Sexually transmitted disease contracted through debauchery occurring in Las Vegas, Nevada. Typically preceded by heavy drinking and suggestive dancing; can also refer to the heavy desire one has to leave Vegas as quick as possible after spending a long trip there full of heavy drinking and suggestive dancing
After leaving Vegas,
Male A: "I haven't been feeling so hot, man."
Male B: "You should probably go to the doctor and get that checked out... wouldn't want to get the Vegas Itch."
you go with your boy toy to a graveyard and both parties dig up the grave of a native american chief and use a bone from his ribcage as a dildo during back to back anal pleasurement. as you both cum you yell a sioux warsong in exctasy.
"yo nigga, lets go down to that cheyanne reservation tonight and bring a 30-rack and a economy size lube tube and do some indian graveyardin'"
"i told this transvestite to suck my dick, but instead he gave me a free indian graveyard and thanks to that motha fucka i can only hobble"