Someone who has been fucked over by God with genetics, (a genetic disgrace.) Gods' Trifecta is when your fat, ugly and bald this especially pertains to a woman with these characteristics. Totally unsavory, The Lord continues to work in mysterious ways.
This woman came shuffling in with the mail today, she received Gods' Trifecta. She was 300 pounds, looked like Mortimer snerd and had the hairline of Peter Boyle.