1. German film director, akin to a modern Ed Wood, who primarily films very bad video game to movie adaptions such as House of the Dead.
2. Something or someone that is extremely bad, untalented, or stupid.
"Uwe Boll is surely the worst director since Ed Wood"
"Man, that shot was Uwe Boll"
"God I'm sucking at this game today, I'm playing like Uwe Boll"