In Italy we use two rude slang words, 1- "scoglionato" that derives from coglioni (same meaning of bollox, testicles) and 2 - "scazzato" (from cazzo, penis)to define the feeling of being either "annoyed to death" or "extremely unsatisfied" because of a certain situation or circumstance.
I guess it might be used in the same way
1 - I felt so bolloxed during the party that I preferred to get back home.
2 - "Hey Joe what's up? You look bolloxed" "I am Frank, things are going in the opposite way I had planned'em"