The act of not quite knowing what is going on; used to express extreme cases of doubt or confusion. Also used as a response to someone asking a favor that you are sure you will not fulfill, similar to the response of "Are you serious?!". Appears several times in The Bible (towards the back) and was used once on live television on April 23, 1998 though scholars furiously debate the accuracy of this claim.
"Major General Samuel Curtis helped the Union win the Battle of Pea Ridge in 1862."
"I need you to clean out the spitoons before you go to the hat store."