Advantages of ESDF over WASD:
1. Three extra keys on the left (Q, A and Z) are now available to a player, which can allow ease of access to a greater range of abilities or commands. The inherent problem with WASD is that it's closer to what's comparable to the "wall" on the left side of a keyboard. The left hand's access to extra commands on the left are reduced, due to there being an excess of unused "blank" space where no keys are located. With ESDF, players still have easy access to the left-most keys on the keyboard, such as Shift, Ctrl, Caps Lock, Tab, and ` (Tilde), while still adding a number of extra keys to bind to various commands.
2. For games that commonly use the number keys and function keys (F1-F12