To hit someone, usually in the face. In this case, "block" is referring to a person's head and you are going to hit then so hard that there head would fall off if not attached!
If that dude over there wolf whistles at my girl again, I swear I'm going to go over and knock his block off
by IKnowTheLingo June 12, 2020
Get the Knock His Block Offmug.