the state in which older women are in when they reach a point in their life in which every single little thing makes them mad/annoyed. Most commonly seen in the workplace where everything seems to be an inconvenience.
Terri: "Have you talked to Mary lately?"
Jenn: "No, she hasn't talked to me in a while after our little argument, she must be having Old Lady Syndrome".
Terri: "That makes sense, she seems to be bothered by everything lately."
Jenn: "No, she hasn't talked to me in a while after our little argument, she must be having Old Lady Syndrome".
Terri: "That makes sense, she seems to be bothered by everything lately."
by fsmbeliever July 23, 2021
a condition where you feel a compulsive need to turn down party invites and/or any other happy event that involves drinking
jay: Hey anthony, come over and let's drink some wine.
anthony: I'm sorry I can't. My booty is very saggy and sticky today. I can't get up my sofa.
jay: You need intervention! That's a sign of O.L.S Old Lady Syndrome.
anthony: I'm sorry I can't. My booty is very saggy and sticky today. I can't get up my sofa.
jay: You need intervention! That's a sign of O.L.S Old Lady Syndrome.
by jiggabuff December 5, 2011
During your period when your vagina feels like it's sagging (eg. like an old lady) and hurts like it might fall off.
Boy: Hey you wanna hook up tonight?
Girl: I have Old Lady Vagina Syndrome (OLVS)
Boy: What?
Girl: If you come near my vagnia, I will decapitate you
Boy: Well that's a definate no then...
Girl: I have Old Lady Vagina Syndrome (OLVS)
Boy: What?
Girl: If you come near my vagnia, I will decapitate you
Boy: Well that's a definate no then...
by tangent to your curves May 24, 2010