one type of firearms that has .45 inches caliber. it's pretty handy when u want to blow someone's head, like when u found out ur bestfriend fucked ur mom... that case, u might u wanna blow both.
"he best go run 'n hide
daddy's got a new .45"
-Sublime-
by whataboutme July 7, 2004
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Loser. 45 is a Loser. 45 is the biggest loser in the history of the United States. Many people used the term 45 to identify the loser who occupied the White House from 2017-2021 because the very sound of the name of the loser in our mouths made us gag and throw up. 45 has become synonymous with being a sore loser, one who makes up lies rather than accept the rank of the world's greatest loser.
by AZgrace April 5, 2021
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Someone who is a crybaby or tries to blame others when they lose or mess up.
Billy was a complete 45 after he lost so bad at the game
by Magicpickle505 April 5, 2021
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A bag of weed costing $45 that some guys like to get cause they think it makes them cooler.
Get out your ligthers boys, we're gettin a 45.
by Bill "Beefy" Jones October 11, 2005
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