one type of firearms that has .45 inches caliber. it's pretty handy when u want to blow someone's head, like when u found out ur bestfriend fucked ur mom... that case, u might u wanna blow both.
by whataboutme July 7, 2004
 Get the 45mug.
Get the 45mug. Loser. 45 is a Loser. 45 is the biggest loser in the history of the United States. Many people used the term 45 to identify the loser who occupied the White House from 2017-2021 because the very sound of the name of the loser in our mouths made us gag and throw up. 45 has become synonymous with being a sore loser, one who makes up lies rather than accept the rank of the world's greatest loser.
by AZgrace April 5, 2021
 Get the 45mug.
Get the 45mug. by Magicpickle505 April 5, 2021
 Get the 45mug.
Get the 45mug. by Bill "Beefy" Jones October 10, 2005
 Get the 45mug.
Get the 45mug.