Sound god awful, but really is a slum-ization of of course my African American friend.
by Homefrog January 30, 2004
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be quiet for a minute my little idiots, which is bastardization of be quiet for a minute my little idiot
Yo, home dawg, be quizzle fo' shizzle ma nizzle, i am tryin' to watch the tube
by Sherin March 18, 2005
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To take part in sexual activities such as masturbation or to have sex with another person. Shizzle meaning "having sex" and nizzle being the vagina or penis etc.
"Go Shizzle the Nizzle"
or
"Shizzle my Nizzle"

8===D (0)
by IDKbecauseREASONS December 9, 2015
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Of course my African American comrad.

A stupid, meaningless phrase that idiotic adolescents use to not offend an african american man to the point that they beat them up.

Stupid
African American Man: Can we go to the fair?
imbecil: Fo' Shizzle my nizzle
by Chesky March 30, 2015
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meaning "for shit my nigga"
this is often said by snoop dogg, aka my daddy.
"you got weed?" "fo shizzle my nizzle"
by confusedspiders January 9, 2017
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I agree with you whole heartedly, my subsaharan brother.
Jimmy asks you to get him a gat. You say “Fo Shizzle My Nizzle.”
by Bobasaursquared April 19, 2020
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