To hand something over; to give up a possession to a robber.
In J. Cole song 'A Tail of Two Cities' ... "Uh, nice watch, run it"
by Optimistic Edit October 27, 2015
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A phrase spammed by stream viewers in chat who were watching Siglemic attempt to beat the Super Mario 64 120 star world record. Due to the many resets, many people believed/trolled that the next attempt was the one to beat the record.

It can be applied to anyone attempting multiple times to beat a record.
*Start of a new run
*X minutes into the run "THIS IS THE RUN"
*Makes a mistake, start over
*Repeat
by Masked One December 27, 2011
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and expression used when taking others posesions in a forceful manner
Bitch run that purse! "please give me your purse"
by Doug999 December 21, 2005
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REALLY BAD Diarrhea

They call it the runs because you gots to "runs" to the washroom before the shit "runs" out of your anus and down your pants (assuming your wearing pants)
I got the runs this one time, but no sweat, I had a diper on.
by S. Li June 1, 2005
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In literature, a Run-on is a shortening of "Run-on sentence". E.g.; "A Run-on". A run-on is a sentence that goes on for too long without proper punctuation.
This is a Run-on: My dad and I went to summer camp along with some friends and we had roasted some marshmallows and cooked some breakfast on the fire and we all slept in a tent.
by kyle.biddle January 20, 2011
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