1 definition by Raym

1. The thing you always died of in The Oregon Trail.

2. An inflammatory disorder of the lower intestinal tract, usually caused by a bacterial, parasitic, or protozoan infection and resulting in pain, fever, and severe diarrhea, often accompanied by the passage of blood and mucus.
Lisa died of dysentery. She can no longer continue the journey.
by Raym November 16, 2005
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