CognitiveFuel's definitions

4-MAX

4-MAX is an abbreviation for 4-Methylaminorex. It's a stimulant stronger than methamphetamine. While it causes no brain damage and last 12 to 16+ hours, it causes lung damage (cough up blood, hospitalizations, death).

Dennis: I tried 4-MAX and now I'm hospitalized! Curse you 4-MAX! More like death dust!

by CognitiveFuel September 11, 2023

PCC

PCC is Pyridinium ChloroChromate. As long as you keep the reaction dry, it oxidizes primary alcohols like ethanol to acetaldehyde and secondary alcohols like isopropanol to acetone. If the reaction is wet, then the aldehyde oxidizes into a carboxylic acid.

I oxidized Ethanol into Acetaldehyde in anhydrous conditions.

CH3CH2OH --PCC--> CH3CHO

by CognitiveFuel September 11, 2023

Phenylacetaldehyde

Phenylacetaldehyde (PAL) is a chemical used in food, fragrances, and in the synthesis of chemicals. Phenylacetaldehyde can be condensed with ethylamine to make Phenylacetaldehyde ethylimine, then reacted with either methylmagnesium iodide in diethyl ether (or dibutyl ether) to yield Ethylamphetamine or with ethylmagnesium chloride in diethyl ether (or dibutyl ether) to yield DEPEA (N,a-DiEthylPhenEthylAmine).

Physical Properties:
Appearance: colorless to pale yellow clear oily liquid (est)
Assay: 95.00 to 100.00
Halogens: Chlorine free
Food Chemicals Codex Listed: Yes
Specific Gravity: 1.02500 to 1.03500 @ 25.00 °C.
Pounds per Gallon - (est).: 8.529 to 8.612
Refractive Index: 1.52500 to 1.53200 @ 20.00 °C.
Melting Point: -10.00 °C. @ 760.00 mm Hg
Boiling Point: 193.00 to 195.00 °C. @ 760.00 mm Hg
Acid Value: 5.00 max. KOH/g
Vapor Pressure: 0.368000 mmHg @ 25.00 °C. (est)
Flash Point: 189.00 °F. TCC ( 87.00 °C. )
logP (o/w): 1.780
Shelf Life: 3.00 month(s) or longer if stored properly.
Soluble in:

alcohol

dipropylene glycol

fixed oils

water, 3026 mg/L @ 25 °C (est)
Insoluble in:

glycerin

Tony: I synthesized Phenyl-2-Propanol (P2Pol) by reacting phenylacetaldehyde (PAL) with methylmagnesium iodide.

by CognitiveFuel September 11, 2023

Chloro(2-thienylmethyl)magnesium

Chloro(2-thienylmethyl)magnesium, or TP-MeMgCl, or 2-thiophenylmethylmagnesium chloride is made from 2-(chloromethyl)thiophene. It's a grignard reagent and an intermediate that can be reacted with acetonitrile to form TP2P (ThioPhenyl-2-Propanone). Then Molecular Formula
C5H5ClMgS
Average mass
156.916 Da
Monoisotopic mass
155.965088 Da

Tony: I synthesized Chloro(2-thienylmethyl)magnesium by reacting 2-(chloromethyl)thiophene with magnesium turnings in diethyl ether. I replaced the diethyl ether with dibutyl ether and reacted it with acetonitrile and hydrolyzed it with hydrochloric acid to yield TP2P (ThioPhenyl-2-Propanone)

by CognitiveFuel September 11, 2023

TP-MeMgCl

TP-MeMgCl is ThioPhenyl-MethylMagnesium Chloride, or Chloro(2-thienylmethyl)magnesium.

Molecular Formula

C5H5ClMgS

Timothy: I synthesized TP-MeMgCl by adding magnesium turnings in anhydrous dibutyl ether with ultrasound and reacted it with acetonitrile and hydrolyzed it with hydrochloric acid to yield TP2P (ThioPhenyl-2-Propanone, 2-Thienylacetone).

by CognitiveFuel September 11, 2023

Thiophene

Thiophene is a chemical that is useful in a lot of stuff. It can be bought or synthesized from butane and sulfer at the vapor phase at 65 °C. Thiophene is an aromatic compound. Thiophene can be chloromethylated by formaldehyde solution and hydrogen chloride at 5 °C or lower to 2-chloromethylthiophene/2-(Chloromethyl)thiophene (TP-MeCl).

Properties
Chemical formula
C4H4S
Molar mass
84.14 g/mol
Appearance
colorless liquid
Density
1.051 g/mL, liquid
Melting point
−38 °C (−36 °F; 235 K)
Boiling point
84 °C (183 °F; 357 K)
Magnetic susceptibility (χ)
-57.38·10−6 cm3/mol
Refractive index (nD)
1.5287
Viscosity
0.8712 cP at 0.2 °C
0.6432 cP at 22.4 °C

Tony: I synthesized 2-chloromethylthiophene from thiophene.

by CognitiveFuel September 11, 2023

4,4'-Difluorobenzophenone

4,4'-Difluorobenzophenone (4,4-Difluorobenzophenone; 4 4-Difluorobenzophenone; 4 4'-Difluorobenzophenone) is an intermediate in the synthesis of the polymer PEEK and is also used in the synthesis of Flodafinil (Flmodafinil, Difluoromodafinil), Fladrafinil (Difluoroadrafinil) and Modafiendz (N-Methyl-Flodafinil, N-Methyl-Flmodafinil).

Tony: I synthesized Flodafinil (Flmodafinil) by using 4,4'-Difluorobenzophenone and sodium borohydride in ethanol, then converting the 4,4'-(Difluorophenyl)methanol to 4,4'-(Difluorophenyl)methyl bromide using Hydrobromic acid and Zinc chloride catalyst. Then reacting it with sodium thioglycolate. Then a few more steps and I got Flodafinil.

by CognitiveFuel September 11, 2023