1 definition by Casey Rexdale

Short for Itis Spot. A designated chill spot for a group of friends to chill and get over the itis (short for niggeritis)
Pronounced "is" not i.s.
"Yo dude, the itis is hittin' me quicktime, let's hit up I.S."

Friend 1: "Yo, ima go home and get some sleep before soccer dude."
Friend 2: "Nah, let's just hit up I.S. for a quick minute."
by Casey Rexdale October 19, 2008
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