1 definition by AnOmenofRapture
MPD also known as "Malarian Penis Disease" is a sexually transmitted disease, which is usually received when one has sex with skanky girls; specifically ones that "Fat John" has been with.
Jeff-"Hey Mike did you ever get with that chick?"
Mike-"Fuck no! Didn't John get with her? She's probably got MPD."
John-"Fuck you guys.."
Mike-"Fuck no! Didn't John get with her? She's probably got MPD."
John-"Fuck you guys.."
by AnOmenofRapture June 2, 2006