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basically it mean do you want to give me head (brain)
you would say it to someone if you wanted them to give you brain, or would use it to ask if you want someone else too.
jack: you on brain?
girl: yeeeaa
jack: sweet come over here now

Jack: you on brain with Danny?
girl: ooh NO
Jack: safee

girl: i am on brain with you.
Jack: waheyyy
by thegemmister January 02, 2010
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Apr 22 Word of the Day
When you eat dirt for the first time and leave your family to build a shack in the woods
Bro since I got dirtpilled on Tuesday I have made sooo many worm friends and made them soo many little houses to get married in. Me? Lonely? No you’re the lonely one u lawn owning freak
via giphy
by ecogoth December 30, 2020
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