A mispelled form of the word llello first started by Antonio Montana.
It is a slang term for the popular drug Cocaine.

Cocaine was first introduced to the US by colombia. nd became most popular around the 70s. The name comes from the name of the coca plant plus the alkaloid suffix -ine. Cocaine was also popularly used for eye, mouth and nasal surgery o numb the area.

yayo is a commonly used drug among many people in the southern california (hollywood scene) and in european countries as a social stimulant.

Cocaine is a central nervous system stimulant and gives the usrs intense feelings of happiness and energy.

Coca- cola ( the soda) originally had cocaine inside. hence the name coca-cola
Pass me an 8 ball of yayo (llello)

cut me a line of yayo

pass me some yay
by Nina O December 30, 2006
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cocaine ... this is the proper spelling yet people believe it is correctly spelled "llello". (usually people who have used the drug several times and belive they know how it works)
I railed a diesel sized line of yayo.
by jgrizz September 1, 2003
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This word became popular after rapper E40 made a song about it. now i cant say he started using it first, but he had a popular song around 97 called "slangin yayo".

it is true that it first appeared in scarface, but i never saw people writing "yayo" before e40.

he is from the san fransisco bay area and sometimes the "east bay" is reffered to san yay. anyway, getting back on point yayo means cocaine.
i hope i dont go back to slangin yayo-slangin what-- yayo-- to get my mayo.

mayo = money
by mooseboy84 August 12, 2004
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Yayo is the spanish word "llello". To make it easier for the english people to pronounce it properly they said "yayo". It sounds the same thing is spanish so STOP TRIPPIN!!!!!!
Man yesterday i sold an ounce of that yayo.
by Brandon October 4, 2004
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Used commonly by some as an expression of concurrence or in a celebratory manner.
Hector: Hey Skinny d, are you going out tonight?
Skinny d: Yayo!
by lanceddd April 26, 2008
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-Cocaine also known as coke.Often a term used bya thug or gangster.
-It is actually a spanish word spelled llello, however, it has been,like many other words, americanized.
Example:
Thug- Yo dawg , can you hook a g up with some yayo?
Thug's homie- Yeah dude, how much you want?
Thug- About a gram yo.
by bizel October 5, 2005
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cocaine you duche bag if you werent aware
As Jasper left for school to get a good education, he snatched some YAYO into his trousers to share with his good pal Horase after school.


Once Beatrice finished her needlepoint, she tried some yayo.

Old uncle fester left his yayo at the premises of the learning facility.
by Meredith Ann O'neil December 15, 2003
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