So if u ask someone "What's poppin' with you". You are asking what is good with that person or what are they doing.
by Ohmod Logan June 23, 2006
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A question posed by a member of the United Blood Nation (UBN) to a pedestrian to which the proper response is:
" Five poppin', six droppin', Crip killer 'til my casket drop. Five alive, six must die, rest in peace to OGI TYE. "
UBN gang member: "What's poppin'?"

you: "Five poppin', six droppin', Crip killer 'til my casket drop. Five alive, six must die, rest in peace to OGI TYE. "
by Jacob's Ladder September 15, 2012
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To say hello to somebody while also asking what's new
Friend 1: Yo Vincent!!! What's poppin??!!
Friend 2: Not much man, but I'm starving. Hey wanna get some chipotle?
by Trixrabbit24 June 25, 2016
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