The typical effeminate (i.e homosexual) way of saying piss off, mainly used by closeted hostile flaming teenagers. Very uncommon among people of the straight persuasion.

A pick me is a woman that is willing to do anything for male approval. She will embarrass or throw other women under the bus to achieve this goal. The unfortunate thing about a pick me is usually the men they are trying to seek approval from are of poor quality and treat women badly, leaving little real benefit for the pick me.

exclamation. a softer way of saying "piss off"

Weekend of Fun (possibly the world's worst acronym...?)