Obese native woman with a loose vagina.
Peter:"Look over there at that dirty wapoo!"
Jamal:"Yeah man, she doesn't shower and I heard her vagina is loose enough to fit a bowling ball.
by Tekid69 January 24, 2011
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Used as part of the Donna and the Dynamos cheer in Mamma Mia: "Dynamos, Dynamites! Sleep all day, and wapoo all night!

"Me and my friends are going wapooing at the Warehouse tonight!"
by dangthisisfun September 4, 2012
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How many shots can you take?
said j-sav
wapoo is to party like an animal until you pass out
"We gon tune it up n wapoo all night, we gonna dance to the beat dance under the sheets"
by Watery drip November 24, 2019
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