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The real meaning is Fuck you.
If you want to say "go take it in the ass" you can also say "Ma vattelo a pigliare in culo!
by Chiara February 03, 2005
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'Fuck off' or 'fuck you' in italian. It is a short form for "va' a fare in culo", literally "go to fuck in the ass" (intending "go get fucked in the ass"). Usually considered vulgar, but used often among (young) friends without offending intention. It can be shortened also as simply "fanculo".
A: "Bei capelli stamattina!" (Nice hairs this morning!)
B: "Vaffanculo!" (fuck you)
by Jero.Potute March 25, 2010
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It's an insult. Anyone who speaks Italian as a first language will tell you that it means "Fuck off". If Italian is not your native language, then you may interpret it as "Fuck an ass" or "Fuck your ass" or any combination of "ass" and "fuck". see previous entries
Marissa yelled "vaffanculo" at me after I tried to appologize for sitting on her goldish.
by Audreyina October 02, 2007
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In Italian, it literally means "Go fuck an ass"
Vaffanculo, testa di cazzo!!!!

Go fuck an ass, dick head!!!!
by milanista May 04, 2004
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"go to do an ass" or "go to do in ass".....
But the real english translation is "Fuck you off", or may be "fuck you" i mean letterally. I say this from my 35 years old of REAL ITALIAN vaffanculo experience!.
Now other examples below..
Fuck you "fottiti"
Fuck Off "vaffanculo"
Fuck You IDIOT "vaffanculo idiota"
You piss me off! "mi hai rotto il cazzo"
Fuck you around "Vai totalmente-complessivamente a fare in culo"
by arturo gatta April 21, 2009
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the phrase "vaffanculo" means "to go fuck yourself". the word "va" means 'go" and fanculo means "fuck you" or "fuck off" so when you put them together it means "go fuck yourself" Many times the Italian hand gesture to complement this word is a straight hand swiftly raised past their ear or it can also resemble a bitch slap.
"hey, so what do you think about the Italian National soccer team after finishing last in their group in the 2010 World Cup in Africa?"

"ma vaffanculo"
by Uleek Midiiq August 16, 2010
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