7
Synonym for cocaine. Lines are referred to as "rippers".

(Uncle Jesse was a character played by John Stamos on the show "Full House". His band was called "The Rippers")
Where's Uncle Jesse?
by RonnieHoffman December 14, 2010
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8
The act of raping a set of twins.
You see the Olsen twins, I just gave them an Uncle Jesse.
by Tanner Family September 24, 2012
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9
When two men are caught rubbing their anuses together.
Uncle Jesse saw the Duke boys rubbing their anuses together down by the crick. Uncle Jesse masterbated while Danny Tanner and Joey rubbed their anuses together.
by Last_Boy_Scout November 12, 2011
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10
A bearded racist from the backwoods of Georgia who guzzled Daisy's huckleberry pies like it ain't no thing. He was played by Denver Pyle, the father of John Stamos. Denver Pyle died a while ago; he died of lung cancer. It probably sucked. He was from Methune, Massachusetts
Denver Pyle? You mean Mr. Methune?
by T Dog Jenkins June 11, 2004
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