Twigger is a variation of the slang "Wigger," which is a white person trying to act all "Nigger" and "Gangsta" to his/her friends to gain street cred. A Twigger is a white person trying to act all "Nigger" and "Gangsta" to his/her friends on Twitter to gain street cred in the virtual world.
Example: Whitie #1: What is up with your little sister acting like a Wigger all the time?

Whitie #2: She thinks it makes her look cool and hip.

Whitie #1: She is going to get her ass whipped one day acting like that in public all the time.....

Whitie #2: She knows that..... so now she just acts like a Twigger on Twitter.
by Crazy43 July 27, 2013
Get the Twigger neck gaiter and mug.
example -

Person 1: «what’s good, twigger? lookin like a twig today!»
Person 2: «i haven’t eaten in 3 months»
by Mtimes4 April 03, 2020
Get a twigger mug for your cat Beatrix.
Another word for tweaker, usually used when the person is skinny due to meth making them as skinny as a twig.
You fuckin twigger.

"What's he doin'?" "Twiggin around."
by BbqBetty February 28, 2019
Get a Twigger mug for your cousin Beatrix.
a person who finds really skinny people attractive; the opposite of a chubby chaser
Ew she only dates really scrawny guys what a twigger.
by Schimmy June 01, 2010
Get a Twigger mug for your cat James.
Bob: That black guy is all hopped up on drugs
Alicia: Ya hes a twigger
Bob: oh I get it
by Shoregirl1984 September 30, 2010
Get a Twigger mug for your buddy Georges.
When your friend who likes to be referred to with nicknames synonymous with trees, branches, and sticks; gets triggered or reeees really hard.
Me: "Emos can be black and darkness"

Branch: "IM; THATS NOT GOTH U IDIOT; IDIOT"

Third Friend: "Wow, Branch is twiggered"
by Gamebird8 April 12, 2020
Get the Twiggered neck gaiter and mug.