Top definition
flipping the fuck out on cocaine, meth, caffine, nicotine, ect.
"Dude did you see Sarah last night she was all twigged out doing cartwheels and shit!"
by hannelore May 11, 2007
Get the mug
Get a twigged out mug for your guy Julia.
2
A term to describe a hella skinny person.
Dude, that chick is hella twigged out! That's nasty!

Lyndsay Lohan is mad twigged out!
by FemmeFatale June 21, 2005
Get the mug
Get a twigged out mug for your brother Jerry.
3
A term referring to a state of mind. Meaning out of it, feeling separated from society and your normal life. Possibly a loss of your self identity. Usually used in context with LSD.
After that crazy acid trip, Sid was really twigged out.
by hoarselady April 05, 2015
Get the mug
Get a Twigged out mug for your guy Manley.