A twiffle is widely considered as someone that is your best friend on the popular social networking site, Twitter.

A jack off buddy (from 'cum' /'come', meaning 'semen', and 'companion'); a friend that you get together with for sessions of solo or mutual masturbation
Variant of: cumpanion (from 'companion' & 'cum'); jack off buddy & wank bud & JO buddy
Similar to: fuck buddy

A small and visually attractive vulva. One that hasn't been worn out or is stinky.

to tickle someone's butthole