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This is the acronym for "That's What I Said." Instead of saying, "That's What She Said" this works in instances where you have said the saying.
"Are you coming?"
"TWIS."
by VCRonna January 29, 2010
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8
(Texting While Intoxicated) - Texting people stuff you wouldn't normally text while under the influence.
Hey did you text me at 3am to go to your house?

Oh yea.... sorry, I was T.W.I.
by JSaintzzz April 17, 2011
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10
Even though i ralphed all over the floor, that last shot was TWI!
by Chillw1nston November 16, 2014
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This Week In Stupid
Beginning line to every TWIS:
Hello everybody and welcome to this week in stupid for (what every day)...
by Rousy Ronald November 03, 2017
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12
Twis means to be under the influence of either drink or drugs
"i'm gunna get twis 2nyt"

"man iz twis"
by MeRkLeMaN July 25, 2009
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13
guy 1: "Dude I texted the admin assistant from the bar last night and it was totally wrong. I think she told our boss"

guy 2: "I told you not to TWI Man!"
by OMGR8US April 20, 2011
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