7
To injure slightly, to sustain a slight injury to (some part of the body), usually while playing a sport.
"The pitcher tweaked his groin on a grounder back to the mound."
by RB Jr. July 18, 2006
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8
To be Up and Fidgity From doing Crystal Meth.
When It's 4 AM U havent slept for days and Ur still wide away your TWEAKING
by Lisa April 09, 2004
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9
1. Customise or modify (something) to suit a particular individual or task
2. Improve (a mechanism or system) by making fine adjustments to it

synonyms: adjustment, modification, alteration, change, adapt, customise
I am going to tweak the design a little more on photoshop
by eslupmaet June 16, 2014
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10
1) to be stimulated by consuming high amounts of caffeine or sugar.
2) to use amphetamine or methamphetamine.
i drank 3 monster drinks and ate a few candy bars at the skatepark and i was seriously tweakin'

a grip of anphetamine pills or a couple of lines of meth can cause you to tweaki all night.
by skaterjack October 05, 2006
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12
1. to go beyond extension, or stretching. as in the truth, a snowboard grab, or a body part.

2. to freak out while you're on drugs. (Usually used in correlation with meth users).
Hey, so you kind of tweaked the story a bit, I don't appreciate that.

Did you see him tweak that sick-ass stale fish?

Dude, I can't skate today-- I tweaked my ankle yesterday falling down 3 flights of stairs.

That Guy is fucking tweaking out. Someone shoot him with a super soaker!
by rustyn! September 26, 2008
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13
To be paranoid/twitchy
To be High
Man, you gotta stop being so tweaky.
Man I was tweaking last night.
by Stewie April 08, 2003
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