The title of a Slick Rick song, the phrase was coined by Ricky D himself, used to describe the reluctance men should take toward women when getting involved with them. After the popularity of Rick's song with the same title, this phrase became popular.

The safeguarding of Earth and other worlds from biological cross-contamination (i.e. billionaires with too much time on their hands).

Also known as “planetary protection.” Planetary protection / quarantine “reflects both the unknown nature of the space environment and the desire of the scientific community to preserve the pristine nature of celestial bodies until they can be studied in detail.”

There are two types of interplanetary contamination. Forward contamination is the transfer of viable organisms from Earth to another celestial body. Back contamination is the transfer of extraterrestrial organisms, if such exist, back to the Earth's biosphere.