A slur used towards transgender and transsexual people, usally transwomen but can also be used towards transmen.
"Hey did you hear, apparently sarah is a tranny!"
"You cant say that! Sarah goes by jake now and is transgender."
by Syke (Koda) July 31, 2017
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An extremely offensive term for a transsexual man or woman, or any of the transgendered community.

On the same level as "nigger", and "cunt" for most people, though, like "dyke", some of the transgendered community are trying to reclaim the word, without much success.
"So your girlfriend's a tranny?" "... Please don't say that... She's a woman, just like you are."
by Ishy March 23, 2006
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Refers to trans people. If it’s a cisgender person using it, it’s a slur. Tranny (when used as a slur) usually refers to women. It’s been kind of reclaimed so some trans people refer to themselves as tranny.
TERF: He’s pretending to be a she. Fucking tranny.

Person: be quiet now please
by anarchism_is_sexy June 21, 2020
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a man like myself who wishes to a female. Its a way of life. We dress like women, act like women, look like women and desire to be a woman.
Im a tranny and im proud of it.
by Michael Rehmey September 9, 2007
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Usually derogitory, a tranny is a transgendered person, transexual, or transvestite.
Man, that tranny is totally hot. I'd hit it.
by Robert D November 24, 2005
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A very offensive slur to transgender people.
Guy 1: Hey look at that ugly tranny over there! Guy 2: May be the ugliest tranny I've ever seen.
by MessedUpSoul February 14, 2017
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