Top definition
Acute dilation of the colon, seen in ulcerative colitis.
"You've got toxic megacolon, ASSFACE!!"
by angelvs August 01, 2007
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Apr 30 Word of the Day
A buzz word being used to refer to creators and influencers forming or encouraging unhealthy relationships with their fans. Usually used in the context of young audiences feeling they have a relationship with the influencer due to the huge amount of the influencer’s content they consume. The influencer in question, however, is unaware of the fan’s existence other than the general knowledge of having fans. Common examples include Dream and his stans. These relationships are exacerbated by the influencers confirming they have more than a creator-to-viewer relationship.

The word is circulating due to various YouTube essays about the phenomenon using the word, and therefore people who enjoy complaining about influencers repeating what they heard in the video in any comments section they can find.
I can’t believe that creator encourages parasocial relationships with his fans...

Man what a parasocial relationship :/
by SodaScarf April 12, 2021
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2
The most dominant ROTO baseball team ever assembled, without collusion, via skilled drafting, shrewd trades, and timely waiver acquisitions. The team took the lead in its 12 team league in mid-April and never looked back, finishing a dominating 20.5 points ahead of the runner-up. Its murderous batting lineup finished 1st in 5 of 6 offensive categories (R, HR, RBI, AVG, OPS) and 2nd in steals. Its dominant pitchers carried the team to 1st in ERA and WHIP, 2nd in SAVES and HOLDS, and 5th in WINS and K's. The indomitable lineup, in its optimal form, was as follows:

C: Brian McCann, ATL
1B: Albert Pujols, StL
2B: Chase Utley, PHI
3B: Aramis Ramirez, CHC
SS: Jose Reyes, NYM
OF: Lance Berkman, HOU
OF: Carlos Lee, TEX
OF: Matt Holiday, COL
UT: Troy Glaus, TOR
Bench: Hideki Matsui, NYY; Jason Varitek, BOS; Corey Patterson, BAL; Kevin Youkilis, BOS; Juan Rivera LAA

SP: Roy Halladay, TOR
SP: Andy Pettitte, HOU
SP: Jered Weaver, LAA
RP: BJ Ryan, TOR
RP: Akinori Otsuka, TEX
RP: Tom Gordon, PHI
P: Todd Jones, DET
P: Joel Zumaya, DET
P: John Lackey, LAA
Bench: Esteban Loaiza, Jon Lester, Mike Stanton

Carlos Lee was acquired in June for Pat Burrell and Ken Griffey Jr. to solidify and streamline the lineup.

Ladies and Gentlemen, the greatest ROTO team of all time!!! Wooooo!!
Man, there is no way we can compete with the Toxic Megacolons. That team is a juggernaut!
by Crew Middle Fork December 06, 2006
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3
A form of diarrhea caused by bacteria Clostridium difficil, that lives in poop.
Aaron can't go out tonight. He's got toxic mega-colon.
by moneypenny07 March 20, 2009
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