1)Someone who is Mentally ill, with dissorders such as Autism or downs syndrome
2)Someone who's behaviour can be related or compared to that of a mentally ill person
That Guy with the huge forehead is a spazz
by C.May June 26, 2004
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A Haliegh or a person who is a total clutz. But makes her/his pain or embarrassment funny to all. But can totally make no sense what so ever.
Haliegh, Alison, My chemical romance, Gerard, frank, ray, bob, mikey, a spazz
by Haliegh April 26, 2008
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When one thing or person ruins something that is otherwise awesome.
Nigel: What the hell, that seagull just shat on the ice cream.

Rodrigo: Well isn't that a spazz in the batter.
by Esteban Blanco February 06, 2011
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failed attempt to keep up or follow along to an exercise routine
Jim's convulsive thrashing to the latest Denise Austin exercise DVD still burned calories but definitely was a stellar example of spazz-ercise.
by Happy Girly of course! January 23, 2011
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Uncontrollably freaking out (may invole flopping around like an awkward fish or just screaming for no APPARENT reason).
Pete Wentz and Brendon Urie: (approaching) Hey guys, hows it going?

Fangirl 1: IJNFGIUNGIMOWIOAOVBNFQWASDFFJGHHDJDKLLLVMNBNSDFINDINFEIFNMIANEFUENDGGNVUNJKS!!!!!!!

Fangirl 2: Dont worry, she's just spazzing out

Fangirl 2, now realizing that she had just talked to Brendon Urie and Pete Wentz says the following and then faints:

GKNFKGNTJGMRORGSGKNLFLWPEORIGFMKMFSEROWEOMRGNSEMFASDFGHJHGFJDSLDKGJHGFKDIRHGTREIOEGJBMVCNBCBM!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
by FANGIRL April 27, 2012
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A spazzed up person with a strange addition for the first 6 letters on a keyboard.
Bro I think I am developing the SPAZZ QWERTY syndrome .
by Laquesha brown April 01, 2017
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