To calm down / loosen up. Typically used when someone is overreacting or in general not being chill.
1. Shakira: AY YO SOMEBODY JUS PULLED ON MAH WEAVE!
2. Mike: Tighten up cuz, ain't nobody pulled on yo weave.
by hastyboomalert July 10, 2012
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1. anything which tightens the vagina see kegel or kegel excercise
2. the act of inserting your penis into a female's anus in order to tighten her vagina, poon
3. the act of inserting any object, dildo, vibrator, vegetable, etc. into a female's anus in order to tighten her vagina, poon
I gave her the old poon tightener and she was screemin so loud, but the ride was so slick up front and behind
by Poonspert May 12, 2004
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a command from one hallion to the next to brighten him/herself -
Well dog, whats the craic?
Feck all, just dyin here!
Rough nite last nite then?
Aye, it was raw!!!
Quit your cryin and tighten up!!
by patjoe September 27, 2012
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A state of altered consciousness induced by narcotics. Most commonly marijuana.
Michael had a Service Huddle with his friends until he got tightened-up.
by Big Mike D. January 28, 2005
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1) To work at an introductory-level tech position.
2) To attempt a feat without knowledge of how it can be done.

Phrase originates from a Westwood College commercial, in which two young videogame designers, dressed in 70s attire, report to their boss that they are "almost done with level 3, and need to tighten up the graphics a little bit."
1) "Once I move back to Arlington I'm gonna tighten up the graphics for Adobe Systems."

2) "I'm almost done with my quadratics homework, I just need to tighten up the graphics a little bit."
by denshuu August 27, 2005
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To give a crossword fanatic a book which contains puzzles which are much, much harder than the ones they are doing right now. It is named after puzzlemaster Will Shortz.
"I just bought Bob that book of Chicago Tribune crossword puzzles. That really oughta tighten his shortz."
by geniusonwheels February 06, 2009
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(participial phrase) the sexual act of grabbing and twisting the head of the penis upon male orgasm in an attempt to increase seminal velocity (and make a cool spiral); the partner performing this act must make a squeaky sound as if a door knob was being tightened
Male 1: My girl was tightening the door knob last night.
Male 2: What?
Male 1: She twisted the head of my penis when I came and I let fly a mighty ejaculate.
Male 2: Does it burn?
Male 1: Yea, but it was worth it. And she's blind now.
by xXxPDxXxn0$c0p3xXx420BL4z3xXx February 23, 2015
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