Urban Dictionary: tie one off

To drink to the point of extreme intoxication. Synonymous with tie one on.

Eric: I think I'm going to tie one off tonight.

by littlebadger June 19, 2009

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to shoot up drugs intravenously

Delina wanted to really "tie one off" so she bought a teener from her dealer.

by aniled June 04, 2009

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The act of having sexual intercourse.

If my date goes well, I plan to tie one off.

by Chumpbuster January 23, 2009

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