Mascot of the best college in the nation - Indiana University. Home of the greatest basketball program in history. Go HOOSIERS!
Also, a nickname for residents of Indiana. People who live in Indiana are called Hoosiers (notice they are not called Boilermakers - mascot of Indiana's rival, Purdue University, which is sucks at life & everything else.)
The Indiana Hoosiers are the best basketball team in the nation.
by Sashlee August 20, 2007
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A malaise that affects a large portion of the population of Indiana. It is characterized by the recognition of the need for a healthier lifestyle, but the adamant rejection of any interventions to improve their state of health. The severely afflicted may present with a number of medical ailments such as Type II Diabetes, Heart Disease, cancer, morbid obesity, and arthritis. These conditions may present even at young ages when the young contract this from their parents.
"Let me get this straight ma'am, you smoke 3 packs a day, drink constantly, eat fast food every meal, never exercise and you wonder why you can't walk more than 15 feet? You obviously have hoosieritis, and it can be deadly"
by blahblahblacksheeps March 16, 2009
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A term given to the male ejaculatory fluid known as semen.
I am going to blow my hoosier on your face.
by Pete12345678 October 12, 2007
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who fucking knows? somebody from Indiana.
1: what in the fuck is a hoosier?
2: I think we'll be alright if we never find out.
by #34 July 19, 2004
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Hoosiers can often be found walking like they have corn cobs up their butt, or like they have been riding horses all day. They are from hillbilly areas like St. Charles, MO, and have a general lack of respect for social decencies: nose-picking, drunken car stealing, having excessively hairy chests, and gambling in public.

They are very picky eaters.
Ryan Green is the biggest hoosier anyone has ever seen. "Narrr, I hate Taka."
by Adam C. Brown August 14, 2006
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A Kentuckian who got lost on his way to Michigan.
"Isn't a Hoosier a person from Indiana?"
by cfisher November 09, 2009
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