A phrase refering to cancer, a very deadly, cellular disease in which normal cells mutate and spread throughout the body or a localized area in the body...
"It's not fair... I don't even smoke and I got the big C..."
by UsurperOfLife April 13, 2005
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cancer, as compared to little c (chlamydia)
It's the big C, and it's neither cocaine, nor crystal.
by gerage247 November 24, 2006
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Big-C is the nickname for fairly large people that have a name that starts with "C". Big-C is just a great person and is bloody huge and can pull bulk babes.
by yaboibigdaddyD March 27, 2018
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The greatest white rapper from Louisiana, him, MC Gurt and N'Ron are bringin white rap back
Fan: Have you heard the latest Big C song? Fuck That Soulja Boy?

Kid: No where can I find it?

Fan: www.myspace.com/bigcfrom985

Kid: Holy shit man, he's right FUCK THAT SOULJA BOY
by Big C from the 985 September 15, 2007
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a large, long, double sided, C shaped dildo that goes in the anus and vagina. The frontal piece (vagina) is a vibrator, and the back (anus) is a piston that goes up and down inside the butt. Off of this C shaped dildo is a cushioned handle for great handling.
Wow, that Big C was great!
Masturbation can't go wrong with a Big C!
by PO PO April 30, 2015
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An emo girl (I think)who has a perverted mind, who lies to everyone and makes up stories to get attention, and claims to have done a dixie cup of speed.
Also has a mentally unstable mother who helps BIG C in making up lies to try to get other people in trouble or to talk to BIG C.
Matt: Did you get your money from her?
Will: No, she's such a BIG C!

by xxonedeadcopxx December 12, 2008
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"This summer i'll fly to Big C for 3 weeks"
by RMCF January 31, 2008
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