Top definition
Used to describe someone that won't shut the fuck up and continues rambling and talking about random shit due to the fact they are under the intoxication of chemical drugs.
"Yo talkbox mcloud shutup."
"Don't let Ian dose cuz then he'll definately talkbox mcloud it all night."

by maki di kiets July 16, 2006
Get the mug
Get a talkbox mcloud mug for your bunkmate James.