Used to initiate conversation with your close friends. Usually followed by "BITCH" or something of the likes, it is a very useable phrase.
BOB: Sup, yo? Bitch? Wat up nigga?
FRED: Call me Bitch again and i'll break ur face!
by not your mum October 06, 2006
Get the sup, yo? neck gaiter and mug.
1. A greeting 2. Hello
Whitey: Hello, and how are you this fine morining sir?

Tyrone: sup yo?
by Tyrone June 04, 2002
Get a sup yo mug for your brother-in-law Manafort.
orignated from the acronym SYDM (shut your damn mouth) but has become the nonsensical phrase for "what's happening/going on?"
"hey, sup yo dog money!"
by f1menu September 05, 2008
Get a sup yo dog money mug for your mate Jovana.
A common greeting between two niggers

However if a white person uses the exact same
phrase when greeting a nigger, they are highly
offended.

1st. Nigger: Yo Sup Nigga?

2nd. Nigger: Hey Bro, Sup wit you nigga?
by Get real, Ya All!!! May 11, 2008
Get a Yo Sup Nigga mug for your dad Abdul.