1. To partake in seducing for sex
2. Slang term for teaching sex
3. New york slang for nasty, dirty sex that you will deffinatly need a shower afterwards

A pick me is a woman that is willing to do anything for male approval. She will embarrass or throw other women under the bus to achieve this goal. The unfortunate thing about a pick me is usually the men they are trying to seek approval from are of poor quality and treat women badly, leaving little real benefit for the pick me.