Shit In, Shit Out: If you're putting shit data into an experiment, you're going to get shit data out.
Your results are bubkes, what did you expect? SISO!
by LogicX March 13, 2010
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a retard or to be retarded. Its name originates from a school called Sisobel for mentally challenged people.
1. George is being siso. (George is being retarded)
2. George is a siso. (George is a retard)
by Jimmy Cracked Corn April 11, 2008
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Siso stands for "spicy in, spicy out". A phrase to help us remember that although spicy things taste good, they may also burn the hell out of your a-hole on the way out.
Person 1: What kind of wings should we get? Inferno?

Person 2: Siso, bro. You don't want an ass like a Japanese flag, do you?

Person 1: Good point, let's get teriyaki.
by juicien June 12, 2011
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Shit in, Shit out.

Making good products bad by putting shit ingredients in to make it cheaper to make.
by drwafu March 01, 2016
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Siso is a person who is simply the best, meaning he’s the strongest, fastest, smartest, most good-looking, and the kindest of all. Everyone wishes to become a Siso one day. Siso is the best in every factor in life he’s the best companion ship you can have and every woman wishes to marry a Siso.
“Wow this guy reminds me so much of Siso”

“Stop trying to act a Siso, you’ll never become one , get over it!”

A7ehhhh
by Golden_Eagle April 16, 2021
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