Means basically anything.

Used to desribe the feelings associated with smoking a drug commonly referred to as water.
Slang, originated in Syracuse, NY by Troy Mims who's tragic death brought a lot of aspirations for change in the area.

Briefly, "the realization that each random passerby is living a life as vivid and complex as your own." Originally from the Dictionary of Obscure Sorrows, which has a lot more beautiful neologism definitions like this you might enjoy.