1. A person that you highly are mad at or want to hurt feelings' of. 2. A strong foul word that really doesnt sound very nice to be called. 3. A reference to use if you really dont like a bitch , a dirty bitch.

Briefly, "the realization that each random passerby is living a life as vivid and complex as your own." Originally from the Dictionary of Obscure Sorrows, which has a lot more beautiful neologism definitions like this you might enjoy.