Refers to being so busy that you don't have time to use a restroom.

Used in the context of passing someone who wants to chat and you do not have time.

A pick me is a woman that is willing to do anything for male approval. She will embarrass or throw other women under the bus to achieve this goal. The unfortunate thing about a pick me is usually the men they are trying to seek approval from are of poor quality and treat women badly, leaving little real benefit for the pick me.