When a person is taking a shit (in a stall), and you see there shoes and they are sick wid it.

when you're hungover as shit after a spending a night drunk as a skunk

A dreadful combination of being sick and shitting at the same time. Stuff coming out both ends basically.

the only word you can use to replace any curse word

The word "sick" pronounced with a speech impediment and/or braces.

the combinatin of the word shit, and fuck

a chick that is the shit

this most easily happens for guys who have recently met a girl and is telling his friends about her and claiming they would like her cause she is the shit and a chick that is good looking