To end someone, especially in a brutal or especially exceptional fashion

When a movie uses its own title in the dialogue.

After giving a great insult that totally makes your friend speechless you slap him with "Roll Credits" meaning that it's over, the audience is leaving and nothing else can be said. It would also be proper to use your hands to demonstrate the rolling of the credits on a screen.

This is also proper to use to term the ending of anything: a night out, a pickup game, or even a relationship"

Last line in every episode of Nickelodeon's "Roundhouse", indicating (duh) that the show's over.

What Margaret thinks is a good idea to jump up and say at the end of every college semester.

inside joke between speedy and funk