Adjective describing anything that is crazy and out of control.
Yo, this fuckin' party is about to get quain!

by Evan Grant October 19, 2008
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Generous, or very parranoid.
"Why the hell were you being so freaking quain today???"
by quain-er-ain-ious May 28, 2005
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The ship name of Quinn Fabray and Blaine Anderson from 'Glee'.
"Oh my god, did you see the Quaine interaction in last night's episode?"
by tremlock February 19, 2012
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A large, fat, juicy vagina. Usually has lots of lips and weighs over 10 pounds.
Dude that gino kid wont fight me, what a huge quaine.
by Tomkat!! July 14, 2009
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