a person that you dont like. generally in a large group of friends, hes the one that nobody likes. he tends to get picked on all the time because he says and does dumb shit

A pick me is a woman that is willing to do anything for male approval. She will embarrass or throw other women under the bus to achieve this goal. The unfortunate thing about a pick me is usually the men they are trying to seek approval from are of poor quality and treat women badly, leaving little real benefit for the pick me.