Top definition
pufo is the abbreviation for Pack Up and Fuck Off. Meaning to get ready and go in a slang way.
Man 1: I'm done
Man 2: Good. Ready to pufo?
by Terrum January 26, 2010
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Apr 24 Word of the Day
A cultural and aesthetic mind-state that prioritizes making money, even as an “underground” or “radical” creator. The work isn’t made for money, but it’s the money that matters the most.
“Dude, his stuff is pretty out there but he’s still pretty Finance Punk.”
by Pop Pop Bienstock April 01, 2021
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3
Noun: A possible unidentified flying object.
Did you see that light in the sky? That was a P.U.F.O.!
by Hartz July 21, 2009
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4
Pack Up and Fuck Off.

British Army slang sometimes used over wireless communications to announce the end of a military exercise. Tidy up and leave.
Military radio conversation:

"Hello 3.1 this is 3, PUFO now, over."
"Hello 3 this is 3.1, roger that, PUFO now, out".
by Nick in Wales October 01, 2019
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